| Cat#: TT3466 | Source#: Rabbit | Type#: Polyclonal | |
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| Applications: WB,IHC,IF/ICC |
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Reactivity: H,M |
| MW.(KDa): 46 |
Isotype: IgG |
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| The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand , osteoprotegerin ligand , both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported , but their full length nature has not been determined. |
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| Western Blot |

Western Blot analysis of various cells using OPG Polyclonal Antibody diluted at 1:1000
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| Western Blot |

Western blot analysis of lysates from 293 cells, using TR11B Antibody . The lane on the right is blocked with the synthesized peptide.
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| Immunohistochemistry |

Immunohistochemical analysis of paraffin-embedded Mouse-lung tissue.
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| IF |
Immunofluorescence analysis of mouse-lung tissue. 1,OPG Polyclonal Antibody (red) was diluted at 1:200 (4℃ overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).3, Picture B: DAPI (blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B
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| Specificity |
OPG Polyclonal Antibody detects endogenous levels of OPG protein. |
| Storage |
Store at -20°C. Stable for one year. |
| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Dilutions |
WB 1:500-2,000; IHC 1:100-300; IF 1:100-300; ELISA 1:20,000
(Optimal dilutions should be determined by the end user)
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| TNFRSF11B ; OCIF ; OPG ; Tumor necrosis factor receptor superfamily member 11B ; Osteoclastogenesis inhibitory factor ; Osteoprotegerin |
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| Size: |
50μL ¥1000 100μL ¥1800 |
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