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β Catenin Rabbit Monoclonal Antibody
Key facts:
Catalog NO:TR8068
Source :Rabbit
Type:Monoclonal
Application:WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA
Reactivity:Human,Mouse,Rat
Isotype:IgG, Kappa
MW(KDa):96kDa
Alternative Names:CTNNB1;CTNNB;OK/SW-cl.35;Catenin beta-1;Beta-catenin;CTNNB;OK/SW-cl.35;PRO2286
Specifications:
Specificity Endogenous

 

Storage Store at -20°C. Stable for one year from the date of shipment.

 

Concentration 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

 

Dilutions

IHC-P 1:1000-1:5000, WB 1:1000-1:5000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200

(Optimal dilutions should be determined by the end user)
Background:
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],
Applications:
Western Blot                                           

Western blot analysis of lysates from HCT116 cells, using β Catenin Rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG antibody was used to detect the antibody.
Immunohistochemistry

 Rat_jejunum
Contact information:
Company:BEI JING TDY BIOTECH CO.,LTD.
Orders:TDYbiotech@163.com
Website:http://www.tdybio.com
Telephone:010-80117836
Address:Zhen Xin Road 36.Changping Distict,Beijing
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig
Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation
Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".