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OPG Rabbit pAb
Key facts:
Catalog NO:TT3466
Source :Rabbit
Type:Polyclonal
Application:WB,IHC,IF/ICC
Reactivity:H,M
Isotype:IgG
MW(KDa):46
Alternative Names:TNFRSF11B ; OCIF ; OPG ; Tumor necrosis factor receptor superfamily member 11B ; Osteoclastogenesis inhibitory factor ; Osteoprotegerin
Specifications:
Specificity OPG Polyclonal Antibody detects endogenous levels of OPG protein.

 

Storage Store at -20°C. Stable for one year.

 

Concentration 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

 

Dilutions

  WB 1:500-2,000; IHC 1:100-300; IF 1:100-300; ELISA 1:20,000 

(Optimal dilutions should be determined by the end user)
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand , osteoprotegerin ligand , both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported , but their full length nature has not been determined.
Applications:
Western Blot           

Western Blot analysis of various cells using OPG Polyclonal Antibody diluted at 1:1000
Western Blot                  

Western blot analysis of lysates from 293 cells, using TR11B Antibody . The lane on the right is blocked with the synthesized peptide.
Immunohistochemistry

Immunohistochemical analysis of paraffin-embedded Mouse-lung tissue.
IF                                                                                                                                                                                                                                                                                                                                                                                                          

Immunofluorescence analysis of mouse-lung tissue. 1,OPG Polyclonal Antibody (red) was diluted at 1:200 (4℃ overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).3, Picture B: DAPI (blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B
Contact information:
Company:BEI JING TDY BIOTECH CO.,LTD.
Orders:TDYbiotech@163.com
Website:http://www.tdybio.com
Telephone:010-80117836
Address:Zhen Xin Road 28.Changping Distict,Beijing
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig
Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation
Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".