010-80117836
276385203@qq.com |
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| Acetyl NF kB P65（K314/K315) Mouse mAb(2A11) |
| NF kappa B p65, NFKB3, p65, p65 NF kB, RELA, TF65, Transcription Factor p65 |
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| Cat#： TDY722 | Source： Mouse | Type： Monoclonal | |
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| Applications: IHC |
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Reactivity: H,R,M |
| MW.(KDa): 65 |
Isotype: IgG1 |
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Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig
NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection. |
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| IHC |
Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Acetyl NF kB P65(K314/K315) （TDY722）Mouse mAb diluted at 1:200.
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| IHC |
Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Acetyl NF kB P65(K314/K315) （TDY722）Mouse mAb diluted at 1:200.
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| Source |
Mouse Monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.
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| Specificity |
The Acetyl NF kB P65(K314/K315) Mouse Monoclonal Antibody can detects endogenous Acetyl NF kB P65(K314/K315) proteins.
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| Storage |
Store at -20°C. Stable for one year from the date of shipment.
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| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
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| Dilutions |
IHC 1:100-200
(Optimal dilutions should be determined by the end user)
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NF kappa B p65, NFKB3, p65, p65 NF kB, RELA, TF65, Transcription Factor p65 |
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| Size: |
TDY722C-50μL ￥1000
TDY722F-100μL ￥1800 |
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| New Product: |
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