010-80117836 
          276385203@qq.com  | 
       
      
        |   | 
        
	  
	  
	
	
	
	 | 
      | 
    
      
         | 
         
      
      
      
        
            
              | IDE/Insulin Degrading Enzyme Mouse mAb(3H4) | 
             
            
              | Abeta-degrading protease antibody, insulin protease antibody, insulinase antibody, insulysin antibody | 
             
            | 
       
      
        |   | 
       
      
     
      
        
          
          
            
                  
                    
                        
                        
                        
                          
						  
                
                  | Cat#: TDY108   |   Source: Mouse   |   Type: Monoclonal   |  | 
                    | 
                 
                
                  
                      
                        | Applications: WB, IHC | 
                          | 
                        Reactivity: H  | 
                       
                      
                        | MW.(KDa): 118  | 
                        Isotype: IgG1  | 
                       
                    | 
                 
               
                
                  
                    Applications:          WB-Western blot     IHC-Immunochemistry       IF-Immunofluorescence     IP-Immunoprecipitation     ChIP-Chormatin Immunoprecipitation 
Reactivity:    H-Human  R-Rat  M-Mouse  Mk-Monkey  Dg-Dog  Ch-Chicken  Hm-Hamster  Rb-Rabbit  Sh-Sheep  Pg-Pig 
  
Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.  
   | 
                   
                 
							  
            
              | 
                 | 
             
            
              
    
        
            | 
             
             
                
                    
                        | Western Blot | 
                        
                            
                        Western blot analysis of 1) Hela, 2) HepG2,with IDE Mouse mAb diluted at 1:2,000.  
                         | 
                     
                
             
             
            
                
                    
                        | Western Blot | 
                        
                            
                        Western blot analysis of Hela, HepG2,with IDE Mouse mAb diluted at 1:2,000.  
                         | 
                     
                
             
             
             
             | 
         
    
 
   | 
             
            
              |   | 
             
           
		                      
                                
                                   | 
                                 
                                
                                  
    
        
            | 
             
             
                
                    
                        | Source | 
                        
                         Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. 
                         | 
                     
                
             
             
            
                
                    
                        | Specificity | 
                        
                         The IDE mouse monoclonal antibody can detect endogenous IDE proteins. 
                         | 
                     
                
             
             
             
            
                
                    
                        | Storage | 
                        
                         Store at -20°C. Stable for one year from the date of shipment.  
                         | 
                     
                
             
             
             
            
                
                    
                        | Concentration | 
                        
                         1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. 
                         | 
                     
                
             
             
             
            
                
                    
                        | Dilutions | 
                        
                         WB 1:1,000 IHC 1:200 
                        (Optimal dilutions should be determined by the end user) 
                         | 
                     
                
             
            
              
             | 
         
    
 
   | 
                                 
                                
                                  |   | 
                                 
                               
		                      
                                
                                   | 
                                 
                                
                                  Abeta-degrading protease antibody, insulin protease antibody, insulinase antibody, insulysin antibody  | 
                                 
                                
                                  |   | 
                                 
                                | 
                         
                        
                      | 
                   
                | 
             | 
            
                
                  |   Size: | 
                 
                
                  TDY108C-50μL ¥1000 TDY108F-100μL ¥1800 | 
                 
                
                  
  | 
                 
                
                  |   New Product: | 
                 
                
                  | 
		  		
				
				 | 
                 
              | 
           
          | 
         
        
          |   | 
         
      |