010-80117836 
          276385203@qq.com  | 
       
      
        |   | 
        
	  
	  
	
	
	
	 | 
      | 
    
      
         | 
         
      
      
      
        
            
              | β-Catenin Mouse mAb(13C6) | 
             
            
              | CTNNB antibody, Cadherin associated protein antibody, b-catenin antibody | 
             
            | 
       
      
        |   | 
       
      
     
      
        
          
          
            
                  
                    
                        
                        
                        
                          
						  
                
                  | Cat#: TDY088   |   Source: Mouse   |   Type: Monoclonal   |  | 
                    | 
                 
                
                  
                      
                        | Applications: WB,IHC | 
                          | 
                        Reactivity: H,M,R  | 
                       
                      
                        | MW.(KDa): 92  | 
                        Isotype: IgG1  | 
                       
                    | 
                 
               
                
                  
                    Applications:          WB-Western blot     IHC-Immunochemistry       IF-Immunofluorescence     IP-Immunoprecipitation     ChIP-Chormatin Immunoprecipitation 
Reactivity:    H-Human  R-Rat  M-Mouse  Mk-Monkey  Dg-Dog  Ch-Chicken  Hm-Hamster  Rb-Rabbit  Sh-Sheep  Pg-Pig 
  
The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.  
   | 
                   
                 
							  
            
              | 
                 | 
             
            
              
    
        
            | 
             
             
                
                    
                        | Western Blot | 
                        
                             
                        Western blot analysis of 1) Hela, 2) 293T, 3) MCF7, 4)Mouse Brain tissue ,3) Rat LiverTissue with β-Catenin mAb diluted at 1:2,000. 
                         | 
                     
                
             
             
            
                
                    
                        | Immunohistochemistry | 
                        
                            
                        IHC staining of human breast cancer tissue with β-Catenin mouse mAb(13C6) diluted at 1:200.  
                         | 
                     
                
             
             
             
             | 
         
    
 
   | 
             
            
              |   | 
             
           
		                      
                                
                                   | 
                                 
                                
                                  
    
        
            | 
             
             
                
                    
                        | Source | 
                        
                         Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. 
                         | 
                     
                
             
             
            
                
                    
                        | Specificity | 
                        
                         The β-Catenin mouse monoclonal antibody can detect endogenous β-Catenin proteins. 
                         | 
                     
                
             
             
             
            
                
                    
                        | Storage | 
                        
                         Store at -20°C. Stable for one year from the date of shipment.  
                         | 
                     
                
             
             
             
            
                
                    
                        | Concentration | 
                        
                         1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. 
                         | 
                     
                
             
             
             
            
                
                    
                        | Dilutions | 
                        
                         WB 1:1,000 IHC 1:200 
                        (Optimal dilutions should be determined by the end user) 
                         | 
                     
                
             
            
              
             | 
         
    
 
   | 
                                 
                                
                                  |   | 
                                 
                               
		                      
                                
                                   | 
                                 
                                
                                  CTNNB antibody, Cadherin associated protein antibody, b-catenin antibody  | 
                                 
                                
                                  |   | 
                                 
                                | 
                         
                        
                      | 
                   
                | 
             | 
            
                
                  |   Size: | 
                 
                
                  TDY088C-50μL ¥1000 TDY088F-100μL ¥1800 | 
                 
                
                  
  | 
                 
                
                  |   New Product: | 
                 
                
                  | 
		  		
				
				 | 
                 
              | 
           
          | 
         
        
          |   | 
         
      |